Progesterone metabolism; investigation of the products of metabolism with human liver in vitro.

نویسنده

  • L M ATHERDEN
چکیده

Gottschalk, A. (1958). In Encyclopedia of Plant Phy8iology, vol. 6, p. 87. Ed. by Ruhland,W. Berlin: Springer-Verlag. Halsall, T. G., Hirst, E. L. & Jones, J. K. N. (1947). J. chem. Soc. p. 1427. Hough, L. & Perry, M. B. (1956). Chem. & Ind. p. 768. Hough, L., Powell, D. B. & Woods, B. M. (1956). J. chem. Soc. p. 4799. Manners, D. J. (1955a). Biochem. J. 61, xiii. Manners, D. J. (1955b). Quart. rev. chem. Soc., Lond., 9, 73. Peat, S., Whelan, W. J. & Hinson, K. A. (1952). Nature, Lond., 170, 1056. Peat, S., Whelan, W. J. & Hinson, K. A. (1955). Chem. & Ind. p. 385. Peat, S., Whelan, W. J. & Lawley, H. G. (1958). J. chem. Soc. p. 729. Somogyi, M. (1952). J. biol. Chem. 195, 19.

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

مکانیسم مولکولی دیس‌لیپیدمی متابولیک در وضعیتهای مقاومت به انسولین

Insulin resistant states are emerging rapidly and lots of efforts have gone into understanding their pathogenesis and major metabolic consequences. Hypertriglyceridemia, a major complication of this metabolic syndrome, seems to be caused by overproduction of lipoproteins (LPs) containing apo B that are rich in triglycerides. Some in vitro and in vivo models have been introduced so as to under...

متن کامل

Recent Technological Advances in Hepatogenic Differentiation of Stem Cells Relevant to Treatment of Liver Diseases

Liver failure, in an acute or chronic form, is a growing health problem ranking as one of the leading causes of death worldwide. Inborn errors of metabolism characterized by defects in hepatic enzymes or other proteins with metabolic functions, such as receptors or transporters accompanied with environmental factors involve etiology and presentation of liver failure. Currently, the only establi...

متن کامل

The metabolism of progesterone by liver tissue in vitro.

Although the administration of progesterone to human beings gives rise to the excretion of pregnanediol in the urine (l), the course and sites of the metabolism of progesterone have not been established. The uterus and ovaries are not essemial for the reduction of progesterone, since a rise in urinary pregnanediol has been demonstrated in men (2, 3) and in hysterectomixed women (4, 5) who were ...

متن کامل

Inhibition of 5-Lipoxygenase inhibitor zileuton in high-fat diet-induced nonalcoholic fatty liver disease progression model

Objective(s): Arachidonic Acid/5-lipoxygenase (AA/5-LOX) pathway connects lipid metabolism and proinflammatory cytokine, which are both related to the development and progression of nonalcoholic fatty liver disease (NAFLD). Therefore, the present study was designed to investigate the role of AA/5-LOX pathway in progression of NAFLD, and the effect of zileuton, an inhibitor of 5-LOX, in this mod...

متن کامل

Imatinib metabolism and disposition in isolated rat perfused liver

Imatinib is an orally administered tyrosine kinase inhibitor which inhibits the Bcr-Abl protein-tyrosine kinase with high selectivity. Imatinib is rapidly absorbed from the gut, after oral intake and has an almost absolute bioavailability of 98%. The metabolism of imatinib is mediated by the cytochrome P450 (CYP) isoenzymes in the liver and gut wall. CGP74588 is a major active metabolite of ima...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

عنوان ژورنال:
  • The Biochemical journal

دوره 71 2  شماره 

صفحات  -

تاریخ انتشار 1959